Contract HPLC Analysis
Automated. Scalable. Reliable.
Custom Analytical Solutions
SDE Chemicals provides flexible HPLC analysis for research, development, and small-scale testing needs. We work with clients to develop or adapt methods, quantify target compounds, and provide clear analytical results without the overhead of a large testing laboratory.
Services can include UV-based HPLC analysis, calibration and quantitation, method development, and custom analytical workflows.
Clear, Reportable Results
Your analysis is delivered with the data needed to understand and use the results. Depending on the project, reports can include method conditions, calibration data, chromatograms, peak integration, calculated concentrations, and relevant QC information.
Need something outside a standard test method? We can work with you to develop an analytical approach around your sample, target compound, and project requirements.
Method Development & Optimization
Not every sample is ready for routine analysis. Complex matrices, overlapping peaks, and unfamiliar compounds can require additional method development before reliable quantitation is possible.
We can evaluate chromatographic conditions and optimize parameters such as mobile-phase composition, gradient conditions, wavelength, flow rate, and sample preparation to improve separation and develop a practical method for your analytical goals.
HPLC Applications
Reaction Monitoring
Track starting-material consumption, product formation, or changes in reaction composition over time.
Impurity & Byproduct Analysis
Separate and investigate secondary peaks, degradation products, and potential process impurities.
Purity Assessment
Evaluate chromatographic purity of research compounds, intermediates, and products.
Quantitative Analysis
Determine target-compound concentrations using external calibration and appropriate QC.
Stability & Degradation Studies
Monitor chemical changes during storage, processing, or controlled degradation experiments.
Process & Formulation Comparisons
Compare samples across reaction conditions, formulations, purification steps, or experimental treatments.
Analytical Support for Your Project
We provide HPLC services for research, product development, process development, and other small-scale analytical needs. Projects can range from straightforward quantitation using an established method to custom method development for new compounds and sample matrices.
Not sure whether your sample is suitable for HPLC? Contact us with your project details and we'll help evaluate the analytical approach.
Based in Ann Arbor, SDE Chemicals provides HPLC analysis throughout Michigan and accepts samples nationwide.
What You Can Expect
Flexible Project Scope
From a small set of research samples to recurring analytical work.
Method-Focused Analysis
Methods can be adapted or developed around your target compound, matrix, and analytical requirements.
Clear Documentation
Receive chromatograms, quantitative results, calibration data, method conditions, and other supporting information as appropriate to the project.
Direct Collaboration
Work directly with us to discuss sample preparation, method requirements, unexpected results, and follow-up analysis.
Have a Sample or Project in Mind?
Tell us about your target compound, sample matrix, expected concentration range, and analytical goals. We'll review your project and help determine an appropriate HPLC approach.
Request an Analysis →