Contract HPLC-UV analysis for research, development, and quality-focused projects — from purity checks and quantitation to method development for compounds that don't fit a standard test.
SDE Chemicals provides contract HPLC-UV analysis for research labs, startups, and manufacturers — from a single research sample to recurring analytical work. Whether you need a quick purity check, a calibrated concentration result, or a method built from scratch for a compound that hasn't been run before, we can help.
Tell us about your compound, sample matrix, and goals, and we'll review the project and let you know directly whether it's a good fit.
UV-based HPLC separation and detection for a wide range of compounds, sample types, and analytical questions.
Determine target-compound concentrations against calibrated standards, with appropriate QC checks along the way.
Standard curves built from your reference material to support accurate, defensible quantitation.
Chromatographic purity assessment for research compounds, intermediates, and finished products.
Separation and investigation of secondary peaks, degradation products, and potential process impurities.
Track starting-material consumption, product formation, or changes in reaction composition over time.
Monitor chemical changes during storage, processing, or controlled degradation experiments.
Build a method from scratch for compounds, matrices, or separations that don't fit an existing procedure.
Refine mobile-phase composition, gradient conditions, wavelength, and flow rate to improve an existing separation.
Dilution, filtration, extraction, and matrix handling scoped to your sample and analytical method.
Results delivered with chromatograms, peak integration, calibration data, method conditions, and calculated concentrations.
A single sample or a small exploratory set — new compounds, early-stage projects, and one-off questions that don't need a large testing lab.
Repeat testing under an established method for ongoing process monitoring, batch checks, or ongoing research programs.
HPLC analysis is useful anywhere you need to separate, identify, or quantify components in a liquid sample. Common questions and projects we support include:
Submit your compound, sample matrix, number of samples, and analytical goal through our quote request form.
We evaluate whether an existing method applies or method development is needed, then provide a scope and price.
Once you approve the scope, samples are run under the agreed method with appropriate calibration and QC checks.
You receive a report with chromatograms, calibration data, peak integration, and calculated results.
Our HPLC systems use UV/Vis detection, suitable for compounds with chromophores that absorb in the ultraviolet or visible range. Detection wavelength is selected based on your target compound's absorbance profile to maximize sensitivity and selectivity.
Most separations run on reversed-phase columns, chosen based on your compound's polarity, stability, and sample matrix. Column chemistry and method parameters can be adjusted during method development to improve resolution.
Quantitative results are generated using external calibration curves built from reference standards you provide or that we source. Calibration range, injection replicates, and QC checks are scoped to the level of confidence your project requires.
Chromatographic data is processed with peak integration and retention-time-based identification. Reports include chromatograms, integrated peak areas, calibration data, calculated results, and the method conditions used to generate them.
We primarily analyze compounds with UV-active chromophores using reversed-phase HPLC-UV. Tell us about your target compound and matrix, and we'll confirm whether it's a good fit.
This depends on your compound's concentration and the analysis required. Small sample volumes are usually sufficient — we'll confirm exact requirements once we understand your project.
Yes. If you have an established method, we can run your samples under it, provided it's compatible with our instrumentation. Send us the method details when you request a quote.
Yes. Method development is one of our core services for compounds, matrices, or separations that don't fit an existing procedure.
Depending on the project, reports can include chromatograms, peak integration, calibration data, calculated concentrations, method conditions, and relevant QC information.
Pricing depends on project scope — number of samples, whether method development is needed, and turnaround requirements. See our HPLC analysis pricing & service tiers for starting prices, or request a quote for your specific project.
Turnaround varies by service — straightforward quantitation is typically faster than method development or validation work. See our pricing page for typical turnaround by service type, or ask when you request a quote.
SDE Chemicals is based in Ann Arbor, Michigan, and works with university research labs, startups, and chemical manufacturers throughout the state. Local sample pickup is available for qualifying projects near Ann Arbor, and we accept samples from clients nationwide.
Learn About Michigan HPLC Services →Tell us about your compound, sample matrix, number of samples, and analytical goal.
SDE Chemicals provides R&D analytical services, based in Ann Arbor, Michigan, with samples accepted nationwide.