Contract HPLC-UV analysis for raw materials, in-process samples, and finished products — built for repeatable, dependable results you can rely on run after run.
Manufacturing doesn't need a research-style, open-ended investigation — it needs consistent, repeatable results on a schedule you can plan around, and a fast answer when something doesn't look right. SDE Chemicals provides contract HPLC-UV analysis for raw materials, in-process samples, and finished products, along with troubleshooting support when an existing method starts producing inconsistent results.
Whether you need a one-time verification, a recurring testing schedule tied to production runs, or help figuring out why a method that used to work no longer does, we can scope the work around your process.
Manufacturing analytical needs tend to repeat, and reliability matters as much as the result itself. These are the areas we see most often.
Repeat testing under an established method, scoped to your production schedule — whether that's weekly raw material checks, batch release support, or ongoing process monitoring. Consistent methods, consistent turnaround.
Evaluate chromatographic purity of raw materials and products, and investigate secondary peaks, byproducts, or unexpected impurities.
Track conversion, intermediate formation, or composition changes across a process step to confirm it's performing as expected.
Build a method where none exists, or diagnose why an existing method is producing inconsistent peaks, retention times, or results.
Send us your existing method — internal, vendor-supplied, or from a specification sheet — along with a description of what's changed: drifting retention times, poor resolution, inconsistent peak areas, or results that don't match expectations. We'll evaluate whether the method can be transferred to our instrumentation as-is or needs adjustment.
This is a common starting point for manufacturers — you don't need a full method-development project to get an existing method running reliably again.
Depending on project scope, results are delivered with the data you need to act on them:
For recurring work, we can also flag trends or shifts across batches worth your attention.
We work with manufacturers across the country — samples ship to us easily, and recurring testing is coordinated on a schedule that fits your production cycle. We're also based in Ann Arbor, Michigan, and offer local sample pickup for qualifying manufacturers in the area.
Learn About Michigan HPLC Services →Yes. Once a method is established, we can support recurring testing on a schedule tied to your production runs, raw material shipments, or batch release needs.
Yes. We can verify identity, purity, or concentration of incoming raw materials against your specifications or a method you provide.
Yes. Send us the existing method and describe what's changed — drifting retention times, poor resolution, or unexpected results — and we'll evaluate what's needed to get it running reliably.
Yes. We regularly work with proprietary formulations and processes and can sign an NDA before reviewing project details if needed.
We provide contract R&D-quality analytical testing, not GMP or ISO-accredited release testing. If your project requires a specific accreditation, let us know and we'll advise whether we're a fit.
Pricing depends on sample volume, testing frequency, and whether method development or troubleshooting is needed. See our HPLC analysis pricing & service tiers for starting prices, or tell us about your project below.
See the full range of HPLC-UV analysis services we offer.
Custom method development, optimization, and troubleshooting.
Starting prices and turnaround for HPLC analysis and method development.
Share what you're working on and we'll let you know directly whether it's a good fit and what it would take to get started.
SDE Chemicals provides R&D analytical services, based in Ann Arbor, Michigan, with samples accepted nationwide.